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Delicious Mexican casserole baked with layers of tortillas, cheese, and toppings
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Mexican Casserole

Creamy, cheesy, and utterly comforting, this Mexican Casserole is the kind of weeknight hero that disappears fast at the dinner table.
Prep Time15 minutes
Cook Time30 minutes
Total Time45 minutes
Course: Main
Cuisine: Mexican
Keyword: Easy
Servings: 6 servings

Equipment

  • Skillet
  • Casserole Dish

Ingredients

Meat and Beans

  • 1 lb lean ground beef
  • 1 small onion, chopped

Tomatoes and Sauce

  • 1 can (10 oz) Ro-Tel tomatoes with green chilies, undrained
  • 1 can (15 oz) Ranch Style beans, drained slightly
  • 1 packet (about 1 oz) taco seasoning
  • 1 can (10.5 oz) cream of chicken soup
  • 1/2 cup water

Toppings

  • 1 bag (10–12 oz) tortilla chips, crushed
  • 2 cups shredded cheddar cheese, divided

Serving Suggestions

  • Sour cream, for serving as needed
  • Salsa, for serving as needed

Instructions

  • Preheat the oven to 325°F (163°C). Lightly grease a 9×13-inch casserole dish and set it aside.
  • In a large skillet over medium heat, add the ground beef and chopped onion. Cook, breaking up the meat with a spatula, until the beef is browned and onions are soft, about 6 to 8 minutes.
  • Drain any excess fat from the skillet to avoid a greasy casserole.
  • Return the skillet to medium heat. Stir in the Ro-Tel tomatoes, Ranch Style beans, and taco seasoning. Mix well so the seasoning coats the meat and beans.
  • Add the cream of chicken soup and water to the skillet. Stir until everything is combined into a thick, saucy mixture. Let it simmer for 5 to 7 minutes, stirring occasionally.
  • Spread a layer of crushed tortilla chips evenly on the bottom of the prepared casserole dish.
  • Spoon half of the meat and bean mixture over the chips in an even layer.
  • Sprinkle with 1 cup of shredded cheddar cheese.
  • Add another layer of crushed tortilla chips, then the remaining meat mixture, smoothing it out evenly.
  • Finish by sprinkling the remaining cheddar cheese over the top.
  • Cover the casserole with foil and bake for 20 to 30 minutes, or until bubbly and the cheese has fully melted.
  • Remove from the oven and allow the casserole to rest for 5 to 10 minutes before slicing.
  • Serve warm with dollops of sour cream and a side of salsa.

Notes

Let the casserole rest after baking for better slicing. You can substitute ground turkey or chicken for a leaner version.