Preheat the oven to 350°F (175°C). Grease a 9-inch springform pan with non-stick spray and set aside.
Pulse graham crackers in a food processor until they are fine crumbs. Transfer crumbs to a bowl.
Add 4 tablespoons brown sugar, 1 teaspoon ground cinnamon, and 5 tablespoons melted butter to the crumbs; pulse or mix until combined. Press the mixture evenly into the bottom of the prepared pan to form a firm crust.
In a separate bowl, combine 1 cup brown sugar, 1 tablespoon ground cinnamon, 6 tablespoons flour, and 6 tablespoons melted butter until crumbly. Set this crumble mixture aside for layering.
In a large bowl, beat the 4 packs of softened cream cheese until fluffy and free of lumps.
Mix in 1 cup granulated sugar, 3 tablespoons flour, and 2 teaspoons vanilla extract until smooth.
Add the 5 eggs one at a time, beating briefly after each addition so the batter stays light but not overmixed. Then add 3/4 cup heavy whipping cream and beat until smooth and silky.
Spoon and spread 1/3 of the cream cheese filling over the crust, then sprinkle with 1/3 of the crumb mixture in an even layer. Repeat layers twice more: another third of filling, another third of crumbs, finishing with the final cream cheese filling layer and the remaining crumble on top.
Place the springform pan in the preheated oven and bake at 350°F for 15 minutes. Without opening the oven, reduce the temperature to 200°F and continue baking for 1 hour and 30 minutes. The center should still have a slight wobble.
Turn off the oven and let the cheesecake cool inside the oven with the door slightly ajar for about 1 hour to prevent cracking. Remove and chill overnight in the refrigerator, uncovered or lightly covered.
For the frosting, beat together 1 tablespoon butter (softened), 1 oz cream cheese (softened), 1/4 teaspoon vanilla extract, 3/4 cup powdered sugar, and 1 1/2 tablespoons heavy whipping cream until smooth and pipeable. Pipe or spread over the chilled cheesecake just before serving.
Notes
For best results, chill overnight and serve with whipped cream and fresh berries.